Synthesizer for oligo- and polysaccharides on solid phase

A synthesizer for automated multistep synthesis on a solid support comprising:

• (a) a reaction vessel,
• (b) a reagent storing component comprising one or more reagent container(s),
• (c) a reagent delivery system configured to establish a fluid communication between each of the one or more reagent container(s) and the reaction vessel, wherein at least two fluid communications are separate of each other,
• (d) an inert gas delivery system comprising a gas container and a gas valve manifold, wherein the gas valve manifold comprises a manifold line and at least three output lines connected to the manifold line,
• wherein the gas container is in fluid communication with the manifold line, the one or more reagent container(s) and the reaction vessel are in separate fluid communications with the output lines of the gas valve manifold, and wherein the at least three output lines are equipped with a means for preventing flow of reagents into the manifold line.