Parallel assembly of chromatography column modules
AssigneeCytiva BioProcess R&D AB
InventorKlaus Gebauer
Life of this patent
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Abstract
A parallel assembly of chromatography column modules, the assembly having one common assembly inlet and one common assembly outlet, each column module comprising a bed space filled with chromatography medium and each column module comprises integrated fluid conduits which when the column module is connected with other column modules are adapted to connect the bed space of the column module with the assembly inlet and the assembly outlet, wherein the total length and/or volume of the fluid conduit from the assembly inlet to one bed space together with the length and/or volume of the fluid conduit from the same bed space to the assembly outlet is substantially the same for all bed spaces and modules installed in the parallel assembly.
Claims20
A stacked assembly of chromatography column modules connected in a rigid housing, the assembly having one common assembly inlet and one common assembly outlet, each chromatography column module comprising a bed space filled with chromatography medium and each chromatography column module comprises a central fluid inlet conduit and a central fluid outlet conduit which when the chromatography column module is connected with other chromatography column modules in the rigid housing are adapted to connect the bed space of the chromatography column module with the assembly inlet and the assembly outlet,
- wherein the total length and/or volume of the fluid conduit from the assembly inlet to one bed space together with the length and/or volume of the fluid conduit from the same bed space to the assembly outlet is substantially the same for all bed spaces and modules installed in the stacked assembly,
- wherein each chromatography column module comprises multiple pieces including at least one structure that provides mechanical rigidity therein;
- and
- wherein said at least one structure further provides a plurality of peripheral fluid conduits therein, wherein each of the plurality of peripheral fluid conduits are fluidically connected to the central fluid inlet conduit and the central fluid outlet conduit.
Dependencies are inferred from the claim text.