Crosslinking submucosal injectate system

An injectate system comprising:

• a crosslinkable gel;
• and
• an electrostatic crosslinker for crosslinking the gel, the crosslinkable gel and the crosslinker forming a crosslinked gel;
• wherein the crosslinkable gel is selected from the group consisting of agarose, alginate, carbomer, carboxymethyl cellulose, collagen, fibronectin, chitosan, chondroitin sulfate, dextran, polyethylene glycol, polyvinylpyrolidone, silicone, poly (hydroxyethyl methacrylate), polyacrylic acid, polyacrylamide, polyvinyl alcohol, gelatin, mucin, heparin, and hyaluronan, and
• wherein the electrostatic crosslinker is selected from molecules comprising divalent elements, and
• wherein the crosslinkable gel and the electrostatic crosslinker are configured to remain flowable to a treatment site and to initiate crosslinking upon the electrostatic crosslinker combining with the crosslinkable gel.