Radiopharmaceuticals and methods of use thereof

A compound consisting of

• a) a targeting moiety, wherein said targeting moiety binds a receptor expressed on a cancer cell and is an agonist of said receptor, and wherein said targeting moiety is a peptide of less than 20 amino acids in length;
• b) a cysteine cathepsin trapping agent (CCTA), wherein said CCTA is an epoxide CCTA, and
• c) a cytotoxic or radioactive moiety,
• wherein said cysteine cathepsin trapping agent is linked either directly or via a linker to said cytotoxic or radioactive moiety, and wherein said cytotoxic or radioactive moiety is linked to the N-terminus of said targeting moiety either directly or via a linker, and
• wherein the log D7.4 of the compound is −2.5 to −4.0.