Use of Lactobacillus paracasei subsp. paracasei K56 in alleviation of intestinal inflammation
AssigneesInner Mongolia Yili Industrial Group Co., Ltd., Inner Mongolia Dairy Tech Res Institute Co Ltd
InventorsWei-Hsien Liu, Wen Zhao, Ting Sun, Wei-Lian Hung, Chao Wu, Guowen Ma, Haibin Zhang
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Abstract
The present invention provides novel use of Lactobacillus paracasei subsp. paracasei K56 in alleviation of intestinal inflammation. Lactobacillus paracasei subsp. paracasei K56 of the present invention has the deposit number CGMCC 15139 or DSM 27447. It was discovered in the present invention that the strain alone was highly efficacious at alleviating intestinal inflammation, reducing inflammatory factors IL-6 and/or TNF-α, promoting the anti-inflammatory factor IL-10, and reducing the tissue damage of colitis.
Claims7
A method for preventing bloody stools caused by colitis, comprising administering to a subject an effective amount of Lactobacillus paracasei subsp. paracasei K56, wherein the Lactobacillus paracasei subsp. paracasei K56 has been deposited at China General Microbiological Culture Collection Center (CGMCC) under a deposit number CGMCC 15139, and also been deposited at German Collection of Microorganisms and Cell Cultures-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ) under a deposit number DSM 27447.
Dependencies are inferred from the claim text.