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US 12,485,141 B2Granted
High molecular iodine concentration compositions, pharmaceutical formulations, preparation and uses
AssigneeI2Pure Corp.
InventorsJack Kessler, Eugene Duan
Life of this patent
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Abstract
Embodiments of high molecular iodine concentration composition and pharmaceutical formulation are disclosed, which may be biostatic persistent, biocidal persistent, and have prolonged biocidal activities against microorganisms for hours after administration of the composition or pharmaceutical formulation. Articles comprising high molecular iodine concentration composition and pharmaceutical formulation, as well as preparation and use of same are also disclosed.
Claims9
A non-aqueous high molecular iodine concentration solution comprising:
- molecular iodine having a concentration of about 1,500 ppm by wt/v,
- glycerin having a concentration of about 99% wt of the total weight of the solution, and
- ethanol having a concentration of about 0.1% to about 1% of the total weight of the solution, wherein the non-aqueous high molecular iodine concentration solution remains stable after 480 days at room temperature.
A high molecular iodine concentration composition comprising:
- molecular iodine having a concentration of about 1,400 ppm to about 150,000 ppm, about 1,400 ppm to about 100,000 ppm, about 1,400 ppm to about 68,000 ppm, about 1,400 ppm to about 66,000 ppm, about 1,400 ppm to about 60,000 ppm, about 1,400 ppm to about 55,000 ppm, about 1,400 ppm to about 50,000 ppm, about 1,400 ppm to about 45,000 ppm, about 1,400 ppm to about 40,000 ppm, about 1,400 ppm to about 35,000 ppm, about 1,400 ppm to about 30,000 ppm, about 1,400 ppm to about 25,000 ppm, about 1,400 ppm to about 20,000 ppm, about 1,400 ppm to about 15,200 ppm, about 1,400 ppm to about 15,000 ppm, about 1,400 ppm to about 10,000 ppm, about 1,400 ppm to about 8,703 ppm, about 1,400 ppm to about 8,000 ppm, about 1,400 ppm to about 5,000 ppm, about 1,400 ppm to about 4,077 ppm, about 1,400 ppm to about 2,000 ppm, about 1,400 ppm to about 1,700 ppm, about 1,274 ppm to about 150,000 ppm, about 1,274 ppm to about 100,000 ppm, about 1,274 ppm to about 68,000 ppm, about 1,274 ppm to about 66,000 ppm, about 1,274 ppm to about 60,000 ppm, about 1,274 ppm to about 55,000 ppm, about 1,274 ppm to about 50,000 ppm, about 1,274 ppm to about 45,000 ppm, about 1,274 ppm to about 40,000 ppm, about 1,274 ppm to about 35,000 ppm, about 1,274 ppm to about 30,000 ppm, about 1,274 ppm to about 25,000 ppm, about 1,274 ppm to about 20,000 ppm, about 1,274 ppm to about 15,200 ppm, about 1,274 ppm to about 15,000 ppm, about 1,274 ppm to about 10,000 ppm, about 1,274 ppm to about 8,703 ppm, about 1,274 ppm to about 8,000 ppm, about 1,274 ppm to about 5,000 ppm, about 1,400 ppm to about 4,077 ppm, about 1,274 ppm to about 2,000 ppm, about 1,274 ppm to about 1,700 ppm, about 1,500 ppm, about 2,000 ppm, about 4,077 ppm, about 4,100 ppm, about 8,200 ppm, about 8,703 ppm, about 15,200 ppm, about 16,500 ppm, or about 33,000 ppm by wt/v;
- an organic carrier having a concentration of no less than about 93.5% wt, no less than about 95% wt, no less than about 98% wt, or no less than about 99% wt of the total weight of the high molecular iodine concentration composition;
- the organic carrier being selected from the group consisting of glycerin, propylene glycol, and combinations thereof;
- and
- ethanol having a concentration of about 0.1% to about 1% of the total weight of the solution, wherein the high molecular iodine concentration composition remains stable after 480 days at room temperature.
2 more elements
Dependencies are inferred from the claim text.