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US 12,485,026 B2Granted
Drug-eluting stent including crystalline cilostazol
AssigneeOtsuka Medical Devices Co., Ltd.
InventorsMasakazu Nagasawa, Hiroshi Ohno, Takafumi Ohyama
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Abstract
Provided is a stent comprising: a stent skeleton; and a deposition layer containing a plurality of layers deposited on the stent skeleton; each layer of the deposition layer comprising crystalline cilostazol, at least one of the plurality of layers comprising a bioabsorbable polymer.
Claims10
A stent comprising:
- a stent skeleton;
- and
- a deposition layer containing a plurality of layers deposited on the stent skeleton;
- each layer of the deposition layer comprising crystalline cilostazol,
- at least one of the plurality of layers comprising a bioabsorbable polymer,
- wherein the deposition layer has at least a first layer and a second layer;
- the content of cilostazol in the first layer, which is closer to the stent, is higher than the content of cilostazol in the second layer, which is more distant from the stent;
- and both layers comprise a bioabsorbable polymer,
- wherein a content of the crystalline cilostazol in the first layer is 55% by mass to 100% by mass, and
- wherein the second layer is an outer and exposed layer.
7 more elements
A stent comprising:
- a stent skeleton;
- and
- a deposition layer containing a plurality of layers deposited on the stent skeleton;
- each layer of the deposition layer comprising crystalline cilostazol,
- at least one of the plurality of layers comprising a bioabsorbable polymer,
- wherein the deposition layer has at least a first layer and a second layer;
- the content of cilostazol in the first layer, which is closer to the stent, is higher than the content of cilostazol in the second layer, which is more distant from the stent;
- and both layers comprise a bioabsorbable polymer, and
- wherein the second layer is an outer and exposed layer.
6 more elements
Dependencies are inferred from the claim text.