Stabilized intraocular drug delivery systems and methods of use

A method comprising:

• obtaining an intraocular drug delivery system configured for implantation into an eye of a subject, the intraocular drug delivery system comprising:
• an intraocular structure and a drug delivery component;
• the intraocular structure comprising an anterior side, a posterior side opposite the anterior side, an edge extending between the posterior side and the anterior side, and a haptic extending outwardly from the edge at an edge-haptic junction, the haptic comprising, at the edge-haptic junction, a relief cut on the posterior side of the intraocular structure;
• and
• the drug delivery component comprising a therapeutic agent and a fixation portion having an opening configured to receive the haptic therethrough, the fixation portion configured to be secured to the relief cut of the haptic such that outward movement of the drug delivery component relative to the edge is inhibited;
• and
• delivering the intraocular drug delivery system into the eye of the subject.