Cleaning, healing and regeneration of tissue and wounds

A system for treating human or animal tissue, comprising:

• a conical body defining a chamber, the conical body extending between a base of the conical body and an outlet nozzle of the conical body, wherein the base has an inlet for flow of a liquid into the chamber and the outlet nozzle is at a conical tip of the conical body and is adapted to generate an output stream of liquid flow from the chamber for treating human or animal tissue;
• an acoustic transducer associated with the conical body and adapted to introduce acoustic energy into the liquid within the chamber whereby the acoustic energy is present in the output stream;
• a gas bubble generator adapted for providing gas bubbles in the output stream that are adapted to be excited by the acoustic energy, wherein the conical body and the outlet nozzle are adapted to have pressure amplitude reflection coefficients with respect to the acoustic energy in liquid within the chamber of −0.95 to −1.0;
• and
• a liquid supply system adapted to supply the flow of the liquid through the inlet at a flow rate of 0.1 to 7 liters/minute,
• wherein the outlet nozzle is adapted to generate an output stream of liquid flow having an average width of 0.25 to 20 mm, wherein the acoustic transducer is adapted to generate acoustic energy having a frequency of 0.1 to 5 MHz, and wherein the gas bubble generator is adapted to provide, in the output stream, bubbles having a radius of 0.5 to 40 μm.