Multifunctional immature dental pulp stem cells and therapeutic applications
AssigneesAvita International Ltd., FundaçãO Butantan
InventorIrina Kerkis
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Abstract
The present invention is directed to therapeutic multifunctional immature dental pulp stem cells (IDPSCs), and IDPSCs multi-lineage compositions. The invention is further directed to the use of IDPSCs and compositions to reduce the risk of and/or treat degenerative diseases or for other medicinal and aesthetic purposes.
Claims16
A cryopreserved composition comprising an isolated population of immature dental pulp stem cells (IDPSCs), wherein the IDPSCs are derived from more than one harvests of an outgrowth of cells from a single dental pulp explant that is mechanically transferred to more than one culture dish, wherein the population of IDPSCs are from 5 or less passages of the more than one harvests of outgrowth of cells from the transferred dental pulp explant, wherein the IDPSCs express beta-3-tubulin and brain-derived neurotrophic factor (BDNF).
Dependencies are inferred from the claim text.