Methods of detection and removal of rhabdoviruses from cell lines
AssigneeTakeda Vaccines, Inc.
InventorJoel R. Haynes
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Abstract
The present disclosure relates to compositions, methods, mixtures, and kits for detecting the presence of, and for removing, a virus from a product produced in an insect cell. The disclosure also relates to proteins, peptides, polypeptides, drug substances, biological products, vaccine antigens, and virus-like particles that are produced in an insect cell and that are free or substantially free of a virus. The disclosure also relates to compositions, methods, assays, and kits for detecting a rhabdovirus in a sample.
Claims27
A kit for detecting a target nucleic acid sequence within a sample, wherein the target nucleic acid sequence comprises at least 50 contiguous nucleotides of SEQ ID NO:
- 1 or the reverse complement of SEQ ID NO:
- 1, wherein the kit comprises one or more primers and at least one probe that is labeled with a fluorophore.
Dependencies are inferred from the claim text.