Composite particles with non-porous hybrid organic-inorganic material
AssigneeWaters Technologies Corporation
InventorsDaniel P. Walsh, Mingcheng Xu, Nicole L. Lawrence
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Abstract
The present disclosure pertains to composite particles with polymer-based cores, which eliminate the high pH failure mechanism of silica-based core-shell silica particles. In various embodiments, a non-porous polymer core is surface modified. In various embodiments, a non-porous hybrid organic-inorganic material is in contact with the modified surface of the core, and a porous inorganic material is in contact with the non-porous hybrid organic-inorganic material. The present disclosure pertains to chromatographic separation devices that comprise such composite particles.
Claims20
A composite particle comprising:
- a non-porous polymer particle core having a modified surface;
- a non-porous hybrid organic-inorganic material in contact with the modified surface;
- and
- a porous inorganic material in contact with the non-porous hybrid organic-inorganic material.
A composite particle comprising:
- a non-porous polymer particle core having a modified surface;
- a non-porous hybrid organic-inorganic material in contact with the modified surface, the non-porous hybrid organic-inorganic material deposited on outer most surface of a porous inorganic material to form a non-porous hybrid organic-inorganic barrier layer on the porous inorganic material on an exterior of the composite particle.
Dependencies are inferred from the claim text.