Extracorporeal bioengineered dual-cell liver regeneration system (EBDLR) and bio purifier therefor

An extracorporeal bioengineered dual-cell liver regeneration (EBDLR) system comprising:

• a multi-layered bio purifier having a plurality of layers, each layer comprising:
• a membrane;
• a first type of cells on a first side of the membrane in a first channel;
• and
• a second type of cells on a second side of the membrane in a second channel;
• a plasma separator to receive blood from a subject via a first pump and separate a plasma component from the blood;
• a first reservoir to collect the plasma component;
• a second pump to move the plasma component from the first reservoir to the multi-layered bio purifier at a predefined flow rate, wherein the multi-layered bio purifier is to distribute the plasma component into the first channel and the second channel of each layer to purify the plasma component;
• a second reservoir to collect the purified plasma component;
• and
• a third pump to infuse the purified plasma component from the second reservoir into the subject.