Back to results
US 12,478,689 B2Granted
Anti-CD19 antibody drug conjugates
AssigneeAbbVie Biotherapeutics Inc.
InventorJames W. Purcell
Life of this patent
Estimating the term…
Abstract
The present disclosure provides anti-CD19 antibody drug conjugates (ADCs), including compositions and methods of using such ADCs.
Claims13
An anti-CD19 antibody comprising:
- a heavy chain variable region comprising a CDR-H1 domain, CDR-H2 domain, and a CDR-H3 domain;
- and
- a light chain variable region comprising a CDR-L1 domain, a CDR-L2 domain, and a CDR-L3 domain, wherein
- the CDR-H1 domain comprises the amino acid sequence GFTFTTYWIN (SEQ ID NO:
- 1,
- the CDR-H2 domain comprises the amino acid sequence NIYPSDSYTNYNQKFKD (SEQ ID NO:
- 2),
- the CDR-H3 domain comprises the amino acid sequence EDYYGSSSYYAMDY (SEQ ID NO:
- 3);
- the CDR-L1 domain comprises the amino acid sequence KASQDVGTAVA (SEQ ID NO:
- 4,
- the CDR-L2 domain comprises the amino acid sequence WASTRHT (SEQ ID NO:
- 5), and
- the CDR-L3 domain comprises the amino acid sequence QQYSTYPLT (SEQ ID NO:
- 6).
12 more elements
Dependencies are inferred from the claim text.