A silver compound preparation, wherein preparation of the silver compound preparation comprises the following steps:
- S1:
- preparing an herbal extract by steam distillation extraction:
- weighing 143-198 g of Portulaca oleracea, 189-232 g of Plumbagella micrantha (Ledeb.) Spach, 53-66 g of peel of Allium sativum, 50-66 g of roots of Spinacia oleracea, and 28-35 g of peel of Citrus reticulata, grinding, adding water to cover the materials, pre-treating ultrasonically for 15-20 min, adding 2-4 L of deionized water, heating and maintaining a resulting mixture in a boiling state, adding 130-150 mL of cider vinegar, and performing reflux condensation to obtain the herbal extract;
- S2:
- adding 33-55 mL of 0.1 M CsOH to 265-286 mL of 1.5-3.2 mM hydroxylammonium chloride (NH2OH·HCl) solution, adding 55.5-76.8 mL of 11-13 mM AgNO3 solution, adding 1.5-2.8 g of sodium dodecyl sulfate, uniformly stirring, performing ultrasonic treatment at 42-54° C. for 33-55 min, placing a resulting mixture for 5-8 h, and then centrifuging at 8,000 rpm, to obtain spherical silver nanoparticles, uniformly mixing the spherical silver nanoparticles with 11-13 g of chitosan, performing vacuum ball milling in a ball mill for 8-11 h, heating in an ultrafast high-temperature Joule heating furnace, uniformly spreading the ball-milled powder containing the spherical silver nanoparticles on conductive substrate graphite paper with a powder layer thickness of 0.8-1.2 mm, setting an initial current density to 200-300 A/cm2, setting a heating rate to 106 K/s, setting a target temperature to 550-630° C., turning on the power, raising the temperature to the target temperature through Joule effect, maintaining the temperature for 40-60 s, taking helium as a cooling medium, after heat preservation is completed, turning off the power, and introducing the helium for quenching, to obtain silver nanoparticles;
- S3:
- preparing nanocapsules:
- weighing 225-235 mL of glycerol, 13.5-17.2 g of gelatin particles, and 12-15 mL of glycol, uniformly mixing by ultrasonic stirring, adding 65-72 mL of deionized water, 1.2-1.6 g of polyethylene glycol 8000, 11.8-13.2 g of the silver nanoparticles prepared in step S2, and 3-5 g of collagen, uniformly stirring, transferring into a three-neck flask, mounting a stirrer, stirring for 50 min, adding cider vinegar to adjust a pH value to 5-6, reacting at 300-400 rpm for 5-6 h, placing for precipitation, removing a remaining solvent after precipitation, washing with distilled water or 75% medicinal alcohol, and vacuum drying for 12 h, to obtain solid powder having the nanocapsules containing the silver nanoparticles;
- and
- S4:
- adding 10.6-13.8 g of the nanocapsules containing the silver nanoparticles that are prepared in step S3 and 1.2-1.5 g of lidocaine to 120-150 mL of the herbal extract prepared in step S1, uniformly stirring, performing ultrasonic treatment for 15-20 min, placing in a vacuum mixing and homogenizing machine, adding 6-8 g of sodium carboxymethylcellulose (CMC) and 35-60 mL of glycerin to the vacuum mixing and homogenizing machine, mixing and stirring for 20-40 min, turning on a vacuum pump of the mixing and homogenizing machine to start vacuuming, vacuum stirring for 45 min, filling a resulting mixture into a tube, and sealing by using a tube sealing machine, to complete the silver compound preparation.