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US 12,478,595 B1Granted
Organoselenium compound for treating cancer
AssigneeImam Mohammad Ibn Saud Islamic University
InventorsTarek Ahmed Yousef, Saad Shaaban, Ahmed A. Al-Karmalawy, Marwa Sharaky, Hussein Ba-Ghazal, Mohamed Alaasar
Life of this patent
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Abstract
A method of treating includes contacting cancer cells with a bis-(organoselanyl urea)aryl agent of Formula (I). The method includes effective inhibition of growth of cancer cells using the bis-(organoselanyl urea)aryl agent of Formula (I) as compared to doxorubicin
Claims10
A method of in vitro inhibition of a cancer cell line, the method comprising:
- contacting cells of the cancer cell line with 1-(4-(methylselanyl)phenyl)-3-((1,3,3-trimethyl-5-(3-(4-(methylselanyl)phenyl) ureido)cyclohexyl)methyl)urea
- wherein the cancer is a cancer cell line is selected from the group consisting of HN9, HuH7, FaDu, MCF7, HEPG2, A549, HCT116, and A375.
Dependencies are inferred from the claim text.