Layered composite for scar treatment and prevention
AssigneeThe Government of the United States, as represented by the Secretary of the Army
InventorKai P Leung
Life of this patent
Estimating the term…
Abstract
A layered composite for scar treatment and prevention, the layered composite including a backing section; a drug matrix section; and a skin-interfacing section. The drug matrix section may be disposed between the back section and the skin-interfacing section. The drug matrix section may include pirfenidone in an amount of from about 1 to about 20 mg/cm2. The layered composite may provide greater than about 75% release of the pirfenidone over a period of about 48 to 72 hours. A method for scar treatment and prevention that includes applying a layered composite as described to a burn wound.
Claims11
A layered composite for scar treatment and prevention, the layered composite comprising:
- a backing section;
- a skin-interfacing section;
- and
- a drug matrix section that (i) is disposed between, and contacts both, the backing section and the skin-interfacing section and (ii) comprises pirfenidone in an amount consisting of from 1 to 2 mg/cm2 in a controlled release matrix base material comprised of an acrylate polymer, wherein the layered composite provides greater than 75% release of the pirfenidone over a period of 48 to 72 hours.
A method for scar treatment and prevention comprising applying a layered composite to a burn wound, the layered composite comprising:
- a backing section, a drug matrix section, and a skin-interfacing section;
- wherein the drug matrix section is disposed between and contacts both the backing section and the skin-interfacing section;
- wherein the skin-interfacing section is disposed against the burn wound;
- and wherein the drug matrix section comprises pirfenidone in an amount consisting of from 1 to 2 mg/cm2 in a controlled release matrix base material comprised of an acrylate polymer.
Dependencies are inferred from the claim text.