Sutures with coatings for detecting and reporting tissue infection
AssigneeEthicon, Inc.
InventorsSasa Andjelic, Leo B. Kriksunov
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Abstract
The present invention is directed to an implantable medical device, comprising: a device body, with at least a portion of said body coated by a sensing coating that comprises an echogenic material or a radiopaque material, or combinations thereof, said sensing coating configured to dissolve or swell in presence of at least one infection biomarker; wherein a portion of said sensing coating is covered by a protective film, forming a protected portion, said protected portion configured not to dissolve or swell in presence of said biomarker and methods of detecting presence of biomarkers in the vicinity of an implanted medical device.
Claims18
An implantable medical device, comprising:
- a) A device body, with at least a portion of said body coated by
- b) a sensing coating that comprises an echogenic material or a radiopaque material, or combinations thereof,
- wherein said sensing coating dissolves or swells in presence of at least one infection biomarker,
- wherein
- 1) a portion of said sensing coating is covered by a protective film that forms at least one protected portion, wherein said protected portion do not dissolve or swell in presence of said biomarker,
- 2) the medical device configured for detection of presence of the infection biomarkers by imaging and detection of dissolution or lack thereof of the unprotected portion in comparison to the protected portion,
- 3) wherein on said device body, a plurality of portions coated by said sensing coating but not coated by said protective film are interspersed with said protected portions, wherein said portions coated by said sensing coating but not coated by said protective film are adjacent to said protected portions.
A method of detecting presence of biomarkers in the vicinity of an implanted medical device, comprising:
- a) coating at least a portion of said device body with a sensing coating that comprises an echogenic material or a radiopaque material, or combinations thereof,
- wherein said sensing coating dissolves or swells in presence of at least one infection biomarker;
- b) coating a portion of said sensing coating with a protective film to form at least one protected portion, said protected portion configured to not dissolve or swell in presence of said biomarker;
- c) detecting dissolution or swelling or lack thereof of said sensing coating in areas not protected by said protective film,
- wherein on said device body, a plurality of portions coated by said sensing coating but not coated by said protective film are interspersed with said protected portions, wherein said portions coated by said sensing coating but not coated by said protective film are adjacent to said protected portions.
Dependencies are inferred from the claim text.