Medical sheet
AssigneeNippon Zoki Pharmaceutical Co., Ltd.
InventorsTakafumi Konishi, Mitsuru Naiki, Toshiko Ujita, Hitoshi Yamamoto
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Abstract
A medical sheet has a cell infiltration suppressing action, including a nonwoven fabric formed of fiber containing an aliphatic polyester, and having a porosity of 50 to 90%. The sheet is very useful because it has an excellent neuroprotective and/or nerve regeneration promoting action, which protects nerves by suppressing the infiltration of inflammatory cells such as macrophages and not giving stimulation that adversely affects nerves because body fluids pass therethrough, by winding around a nerve at a peripheral nerve injury site.
Claims18
A sheet comprising a nonwoven fabric formed of fiber containing a biodegradable aliphatic polyester, wherein a porosity of the sheet is 50 to 80% and the sheet has a cell infiltration suppressing action,
- wherein a thickness of the sheet is 30 to 70 μm,
- wherein the biodegradable aliphatic polyester contained in the fiber has a molecular weight distribution in which a maximum value exists in at least two or more regions of the molecular weight,
- wherein the sheet further contains a drug, and
- wherein a density of the sheet is 200 to 800 mg/cm3.
Dependencies are inferred from the claim text.