Aryl hydrocarbon receptor activators

A compound of the formula:

• or a tautomer thereof, a stereoisomer thereof, a hydrate thereof, or a pharmaceutically acceptable salt thereof, wherein:
• Q1 is an optionally substituted C6-C10 aryl;
• optionally substituted C5-C10 heteroaryl;
• optionally substituted C5-C10 heterocyclyl;
• optionally substituted C1-C10 alkyl, or optionally substituted C3-C10 cycloalkyl;
• Z is C;
• R1 is H or halogen;
• R2, R3, and R4 are independently H, halogen, CN, optionally substituted C1-C10 alkyl, optionally substituted C3-C10 cycloalkyl, optionally substituted C1-C6 alkoxy, SO2R5, CO2R5, or CONR5R6, or any one of R1 and R2, R2 and R3, and R3 and R4 pairs, together with the carbon atoms to which they are attached, forms an optionally substituted a five- or six-membered cycloalkenyl, heterocyclenyl, aryl or heteroaryl;
• R5 and R6 are independently H, optionally substituted C1-C10 alkyl, or optionally substituted C3-C10 cycloalkyl, or R5 and R6, together with the nitrogen atom to which they are attached, form an optionally substituted 5-membered ring or an optionally substituted 6-membered ring;
• R7, at each occurrence, is independently H, halogen, CN, optionally substituted C1-C10 alkyl, optionally substituted C2-C6 alkenyl, optionally substituted C1-C10 heteroalkyl, optionally substituted C1-C10 heterocyclyl, optionally substituted C6-C10 aryl, optionally substituted C5-C10 heteroaryl, optionally substituted C1-C6 alkoxy, optionally substituted C1-C6 cycloalkyloxy, OCF3, NR5R6, SCF3, or C(O)NR5R6;
• and
• m is an integer from 1 to 7.