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AssigneeThe Regents of the University of California
InventorsYujia Liu, Marc Madou, Roya Shiri, Alfonso Shin, Snehan Peshin
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The present invention is directed to a recirculation system for use in microfluidic centrifugal disc platforms for reusing and mixing an entire sample. The present invention features a system comprising a reservoir, an input channel, a detection array, a pressure chamber, and a recirculation channel connecting the pressure chamber to the reservoir. The recirculation channel may have a resistance lower than the channel upstream resistance. When the CD platform spins at a high RPM, the liquid may be directed from the reservoir into the pressure chamber. When the RPM of the CD platform decreases rapidly, the liquid may be directed from the pressure chamber through the channel and through the recirculation channel to the reservoir, such that the liquid travels through the recirculation channel faster than the liquid travels through the channel.
A system (100) for observing and recirculating liquid in a microfluidic centrifugal disc (CD) platform (160) in order to recycle a sample contained in the liquid, the system (100) comprising:
A method for observing and recirculating liquid in a microfluidic CD platform (160) in order to recycle a sample contained in the liquid, the method comprising:
Dependencies are inferred from the claim text.