Oxygenator and method for manufacturing same
AssigneeTerumo Kabushiki Kaisha
InventorsTakeshi Sato, Renjo Takama
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Abstract
An oxygenator having a plurality of porous hollow fiber membranes for gas exchange to treat blood is manufactured by dissolving a silicone compound in an organic solvent having a surface tension of less than 70 dyn/cm to prepare a coating solution, and bringing an inner surface of the hollow fiber membranes into contact with the coating solution under a negative pressure of 50 hPa or more and 150 hPa or less to form a silicone compound-containing coating layer on the inner surface. An antithrombotic polymer compound-containing coat can be provided directly on an outer surface of the hollow fiber membranes.
Claims10
A method for manufacturing an oxygenator having a plurality of porous hollow fiber membranes for gas exchange, the method comprising the steps of:
- dissolving a silicone compound in an organic solvent having a surface tension of less than 70 dyn/cm to prepare a coating solution;
- and
- bringing an inner surface of the hollow fiber membranes into contact with the coating solution under a negative pressure of 50 hPa or more and 150 hPa or less to form a silicone compound-containing coating layer on the inner surface.
A method for manufacturing an oxygenator having a plurality of porous hollow fiber membranes for gas exchange, the method comprising the steps of:
- dissolving a silicone compound in an organic solvent having a surface tension of less than 70 dyn/cm to prepare a coating solution;
- exposing an inner surface of the hollow fiber membranes to the coating solution under a negative pressure of 50 hPa or more and 150 hPa or less;
- and
- drying the organic solvent;
- wherein the exposing and drying steps are sequentially repeated a plurality of times to form a silicone compound-containing coating layer on the inner surface.
Dependencies are inferred from the claim text.