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US 12,472,284 B2Granted
Structured gels
AssigneeUniversity of Southampton
InventorsRichard Oreffo, Jonathan Dawson, Nicholas Evans, Roxanna Sharon Ramnarine Sanchez
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Abstract
The invention relates to a method for assembling a clay-nanoparticle gel suitable for loading with one or more molecule species such that they are spatially structured therein, and a method for forming a clay-nanoparticle gel comprising one or more spatially structured molecule species. The invention further relates to structured clay nanoparticle gel and their use, for example in treatment.
Claims18
A method for forming a spatially structured clay-nanoparticle gel comprising one or more spatially structured molecule species, the method comprising:
- forming a spatially structured clay-nanoparticle gel comprising protein, by
- providing a colloidal solution of clay-nanoparticles, and
- immersing the colloidal solution of clay-nanoparticles into an aqueous assembly solution without mixing and allowing the colloidal solution of clay-nanoparticles to set via protein diffusion into a gel within the aqueous assembly solution,
- wherein a protein is provided in the aqueous assembly solution prior to, concurrently, or after the immersion of the colloidal solution of clay-nanoparticles into the aqueous assembly solution, thereby forming a clay-nanoparticle gel comprising the protein;
- and
- loading the clay-nanoparticle gel comprising protein with additional molecules comprising the step of immersing the clay-nanoparticle gel comprising protein into an aqueous loading solution,
- wherein the additional molecules are provided in the aqueous loading solution prior to, concurrently, or after the immersion of the clay-nanoparticle gel comprising protein into the aqueous loading solution, such that the additional molecules are absorbed into the clay-nanoparticle gel and spatially structured therein.
4 more elements
Dependencies are inferred from the claim text.