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US 12,472,227 B2Granted
Pharmaceutical compositions and use thereof for relieving resistance due to cancer chemotherapy and enhancing effect of cancer chemotherapy
AssigneeRise Biopharmaceuticals Inc.
InventorsJya-Wei Cheng, Hsi-Tsung Cheng, Hui-Yuan Yu, Su-Ya Hsu, Wei-Chen Lee
Life of this patent
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Abstract
The present invention provides a novel chemokine receptor antagonistic modified peptide. The novel chemokine receptor antagonistic modified peptide can be combined with a chemotherapeutic drug for treating cancer, especially for treating drug-resistant cancer, and inhibiting tumor growth more effectively.
Claims3
A method of treating a gemcitabine-resistant pancreatic cancer, comprising:
- administering a chemokine receptor antagonistic modified peptide combined with gemcitabine in a therapeutically effective amount to the gemcitabine-resistant pancreatic cancer subject in need thereof,
- wherein the chemokine receptor antagonistic modified peptide is ONCO P-8 set forth in SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.