# US 12,472,099 B2 · Medical device and ocular implant for treatment of ocular disorders > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,472,099 B2 - Document ID: US12472099B2 - Status: Granted - Kind: B2 - Application number: 19/235,272 - Filed: 2025-06-11 - Published: 2025-10-09 - Granted: 2025-11-18 - Earliest claimed: 2022-12-13 - Assignees: Hexiris Inc. - Applicants: Hexiris Inc. - Inventors: Houfar Sekhavat; Nir Shoham-Hazon - Web page: https://patentgrep.com/patent/US12472099B2 ## CPC - A61F 9/00781: {Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment (drainage implants in general A61M27/002)} - A61B 17/3468: {for implanting or removing devices, e.g. prostheses, implants, seeds, wires (devices for implanting seeds A61M37/0069)} - A61B 2017/00367: {Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like} - A61B 2017/00477: {Coupling (A61B2017/0046 takes precedence)} - A61F 2/148: {Implantation instruments specially adapted therefor} - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract A medical device for office-based/operating room bleb forming minimally invasive glaucoma surgeries. The medical device includes a proximal segment for grasping by a user, a distal segment that includes a piercing member coupled to and extending from the distal segment, wherein the piercing member is configured to contain and deliver an ocular implant into an eye tissue layer to obtain a channel, wherein the proximal segment and the distal segment being configured to couple to each other at a pivot point between an unlocked configuration and a locked configuration, and wherein in the unlocked configuration, the proximal segment and the distal segment are rotatable relative to each other about a rotation axis at the pivot point. ## Claims ### Claim 1 A medical device, comprising a) an ocular implant configured to facilitate aqueous humor outflow from an anterior chamber of an eye; b) a piercing member for penetrating ocular tissue and housing the ocular implant prior to delivery; c) a release structure associated with the piercing member and operable to deliver the ocular implant from the piercing member, the release structure comprising an internal casing disposed within a distal cavity of the medical device and coupled to the piercing member; and d) an actuator operatively associated with a displacement mechanism, the displacement mechanism comprising one or more movable elements responsive to actuation and operable to engage the release structure, wherein actuation of the actuator in a first direction causes the displacement mechanism to engage the release structure, and subsequent actuation of the actuator in a second direction causes coordinated retraction of the release structure and the piercing member to release the ocular implant from the piercing member and position the implant within the eye. ### Claim 2 (depends on 1) The medical device of claim 1, wherein the displacement mechanism includes a plurality of projections configured to engage with the internal casing and operatively coupled to the actuator. ### Claim 3 (depends on 1) The medical device of claim 1, wherein the actuator is a slider, a trigger, or a wheel. ### Claim 4 (depends on 1) The medical device of claim 1, wherein the actuator comprises a return mechanism configured to urge the actuator toward the second direction after actuation in the first direction. ### Claim 5 (depends on 4) The medical device of claim 4, wherein the return mechanism includes a spring assembly connected between the actuator and a distal segment of the device, the spring assembly being extendable along a longitudinal axis of the distal segment upon movement of the actuator in the first direction and retractable upon release of the actuator to return the actuator in the second direction. ### Claim 6 (depends on 2) The medical device of claim 2, wherein the internal casing includes engaging elements positioned at a proximal portion thereof, and the projections include complementary engaging elements located at distal portions thereof. ### Claim 7 (depends on 6) The medical device of claim 6, wherein engagement between the internal casing and the projections produces audible feedback in the form of one or more clicking sounds. ### Claim 8 (depends on 6) The medical device of claim 6, wherein the projections include prongs extending distally, and the complementary engaging elements are located on distal regions of the prongs. ### Claim 9 (depends on 8) The medical device of claim 8, wherein the prongs are formed of a resilient material and are deformable radially outward when contacting a superior surface of the internal casing, such that distal ends of the prongs engage with corresponding depressions formed in the internal casing. ### Claim 10 (depends on 1) The medical device of claim 1, further comprising a stopper positioned within the piercing member, the stopper including a distal-facing contact surface configured to abut a proximal end of the ocular implant to restrict movement of the implant during retraction of the piercing member. ### Claim 11 (depends on 1) The medical device of claim 1, wherein the piercing member has a diameter corresponding to a needle gauge between 23 and 30. ### Claim 12 (depends on 1) The medical device of claim 1, wherein the ocular implant comprises a first engaging element and a second engaging element positioned on a surface of the elongated body, each of the first and second engaging elements extending away from the body and being compressible toward the body. ### Claim 13 (depends on 1) The medical device of claim 1, wherein the first and second engaging elements are angled toward one another. ### Claim 14 (depends on 1) The medical device of claim 1, wherein the first and second engaging elements are spaced apart by a distance between about 1.8 mm and about 2.2 mm. ### Claim 15 (depends on 1) The medical device of claim 1, wherein the piercing member has a length between about 8.0 mm and about 20.0 mm. ### Claim 16 (depends on 1) The medical device of claim 1, further comprising a proximal segment configured for grasping by a user and a distal segment including the piercing member, wherein the proximal segment is separable from the medical device. ### Claim 17 (depends on 1) The medical device of claim 1, wherein the ocular implant comprises a biocompatible, flexible material and includes a lumen extending through the elongated body.