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US 12,472,057 B2Granted
Tubular prostheses
AssigneesHumacyte, Inc., Yale University
InventorsLaura Niklason, Angela Huang, Liping Zhao, Shannon Dahl
Life of this patent
Estimating the term…
Abstract
Tubular prostheses are provided for use in airways, upper digestive, and urinary tracts. Each of these uses has its own specific sets of biological specifications, based on what it must contain and exclude and the physical and chemical pressures and stresses to which it is subjected. The prostheses may be made from allogeneic cells. Thus they can be manufactured and stored prior to an individual's personal need arising.
Claims7
An artificial esophagus for replacement of damaged tissue by implantation, said artificial esophagus comprising:
- substantially acellular, human extracellular matrix formed as a tube of greater than 10 mm diameter, wherein the artificial esophagus has a suture retention strength of greater than 150 grams.
Dependencies are inferred from the claim text.