US 12,471,992 B2Granted

Laser combination with in vivo target feedback analysis

AssigneeGyrus ACMI, Inc.

InventorsKurt G. Shelton, Sergey A. Bukesov

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Abstract

A laser can be controlled based on different tissue compositions, such as in real time. After a first time period, a first composition of a in vivo target site can be identified. Based on the first composition, a plurality of lasers can be controlled to emit light at a first wavelength where controlling includes activating a first combination of the plurality of lasers. After a second time period, a second composition of the in vivo target site different from the first composition can be identified. Based on the second composition, a plurality of lasers can be controlled to emit light at a second wavelength, such as can include activating a second combination of the plurality of lasers. The first combination of the plurality of lasers can be different from the second combination of the plurality of lasers.

Claims12

Dependent claims

A system comprising:

a plurality of laser sources, wherein a first laser source of the plurality of laser sources is configured to emit light having a first wavelength range and a second laser source of the plurality of laser sources is configured to emit light having a second wavelength range different from the first wavelength range to an in vivo target site;
an endoscope having a proximal portion and a distal portion, the distal portion being configured to be inserted into a location in proximity to the in vivo target site;
a controller configured to:
analyze a first signal from the in vivo target site to determine a first depth at the in vivo target site, wherein the first depth relates to a first penetration depth of first emitted light into the in vivo target site;
and
based at least in part on the first depth at the in vivo target site, selectively activate the first laser source so as to treat the in vivo target site;
and
wherein the controller is further configured to:
receive a second signal from the in vivo target site;
analyze the second signal to determine a second depth at the in vivo target site, wherein the second depth relates to a second penetration depth of second emitted light into the in vivo target site;
and
based at least in part on the second depth of the in vivo target site, selectively activate the second laser source so as to adjust a treatment effect at the in vivo target site.

9 more elements

A system comprising:

a plurality of laser sources, wherein:
individual ones of the plurality of laser sources are configured to emit light having different wavelengths to an in vivo target site;
a first laser source of the plurality of laser sources is configured to emit light having a first wavelength range and a second laser source of the plurality of laser sources is configured to emit light having a second wavelength range different from the first wavelength range to the in vivo target site;
an endoscope having a proximal portion and a distal portion, the distal portion being configured to be inserted into a location in proximity to the in vivo target site;
a controller configured to:
analyze a first signal from the in vivo target site to determine a first depth at the in vivo target site, wherein the first depth relates to a first penetration depth of first emitted light into the in vivo target site;
and
based at least in part on the first depth at the in vivo target site, selectively activate the first laser source so as to treat the in vivo target site;
wherein the controller is further configured to:
receive a second signal from the in vivo target site;
analyze the second signal to determine a second depth at the in vivo target site, wherein the second depth relates to a second penetration depth of second emitted light into the in vivo target site;
and
based at least in part on the second depth of the in vivo target site, selectively activate the second laser source and cause the first emitted light to combine with second emitted light so as to adjust a treatment effect at the in vivo target site.

10 more elements

A system comprising:

a plurality of laser sources, wherein a first laser source of the plurality of laser sources is configured to emit light having a first wavelength range and a second laser source of the plurality of laser sources is configured to emit light having a second wavelength range different from the first wavelength range to an in vivo target site;
an endoscope having a proximal portion and a distal portion, the distal portion being configured to be inserted into a location in proximity to the in vivo target site;
a controller configured to:
analyze a first signal from the in vivo target site to determine a first depth at the in vivo target site, wherein the first depth relates to a first penetration depth of first emitted light into the in vivo target site;
and
based at least in part on the first depth at the in vivo target site, selectively activate the first laser source so as to treat the in vivo target site;
receive a second signal from the in vivo target site;
analyze the second signal to determine a second depth at the in vivo target site, wherein the second depth relates to a second penetration depth of second emitted light into the in vivo target site;
and
based at least in part on the second depth of the in vivo target site, selectively activate the second laser source so as to adjust a treatment effect at the in vivo target site;
an optical component configured to:
receive light emitted from one of the first laser source or the second laser source;
and
direct the received light to the in vivo target site.

11 more elements

Dependencies are inferred from the claim text.

Facts

Application: 18/046,534Filed 14 Oct 2022 · us provisional application
Priority: 22 Oct 2021
Published: US 2023/0131637 A127 Apr 2023
Granted: 18 Nov 2025
Term ends: Not estimatedThe source records don’t support an estimate.

Classification27 codes

A61B 1/000094
Of image signals during a use of endoscope: extracting biological structures
A61B 18/24
The beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor: with a catheter
A61B 1/00009
Characterised by electronic signal processing: of image signals during a use of endoscope
A61B 1/043
Combined with photographic or television appliances: for fluorescence imaging