Systems and devices for detecting coronary artery disease using magnetic field maps

A system for determining a presence, an absence, or a likelihood of coronary artery disease in an individual, comprising:

• (1) a sensing device configured to sense a magnetic field associated with an individual, wherein the device comprises:
• a. a movable base unit;
• b. an arm having a proximal end and a distal end, the proximal end being coupled to the moveable base unit by a first joint, the first joint configured so that the arm moves relative to the movable base unit with at least one degree of freedom;
• and
• c. an array of one or more optically pumped magnetometers coupled to the distal end of the arm, the array of one or more optically pumped magnetometers configured to sense the magnetic field associated with the individual;
• and
• (2) a non-transitory computer readable medium encoded with a computer program comprising instructions executable by a processor configured to cause the processor to:
• i. receive, from the sensing device, a first magnetic field associated with a heart of the individual at a first time when a R-wave is recorded, wherein the first time when the R-wave is recorded corresponds to a depolarization phase of the heart of the individual;
• ii. generate a first electromagnetic field map based on the first magnetic field associated with the heart of the individual at the first time, wherein the first electromagnetic field map is a R-wave electromagnetic field map;
• iii. identify a first negative electromagnetic dipole and a first positive electromagnetic dipole in the first electromagnetic field map;
• iv. receive, from the sensing device, a second magnetic field associated with the heart of the individual at a second time when a T-wave is recorded, wherein the second time when the T-wave is recorded corresponds to a repolarization phase of the heart of the individual;
• v. generate a second electromagnetic field map based on the second magnetic field associated with the heart of the individual at the second time, wherein the second electromagnetic field map is a T-wave electromagnetic field map;
• vi. identify a second negative electromagnetic dipole and a second positive electromagnetic dipole in the second electromagnetic field map;
• vii. determine a first angle based on the first negative electromagnetic dipole and the first positive electromagnetic dipole, and a second angle based on the second negative electromagnetic dipole and the second positive electromagnetic dipole;
• and
• viii. determine the presence or the absence the coronary artery disease in the individual, based at least in part on (i) whether the first angle differs from the second angle by 100 degrees to 170 degrees, or (ii) whether there is a presence of a third electromagnetic dipole in either the first electromagnetic field map or the second electromagnetic field map.