Back to results
US 12,467,835 B2Granted
Systems and methods for monitoring tissue sample processing
AssigneeVentana Medical Systems, Inc.
InventorsJefferson Curtis Taft, David Chafin, Michael Otter, Benjamin Stevens
Life of this patent
Estimating the term…
Abstract
A tissue sample that has been removed from a subject can be evaluated. A change in speed of the energy traveling through the sample is evaluated to monitor changes in the biological sample during processing. The monitoring can detect movement of fluid with the sample and cross-linking. A system for performing the method can include a transmitter that outputs the energy and a receiver configured to detect the transmitted energy.
Claims16
A system, comprising:
- a processing unit including an acoustic monitoring device;
- a tissue preparation unit capable of (i) applying one or more substances to a biological sample;
- and (ii) performing a fixation process on the biological sample;
- and
- a computing device communicatively coupled to the processing unit and the tissue preparation unit, where the computing device is configured to evaluate a speed of the acoustic waves-traveling through the biological sample based on a time of flight of the acoustic waves, and wherein the computing device includes instructions which, when executed, cause the processing system to:
- (i) apply, using the tissue processing unit, one or more substances to the biological sample;
- (ii) monitor diffusion of the one or more substances through at least a portion of the biological sample using the acoustic monitoring device;
- and
- (ii) perform, using the tissue processing unit, a fixation process on the biological sample after the one or more substances have diffused through the at least the portion of the biological sample.
6 more elements
Dependencies are inferred from the claim text.