Leptin compositions and methods of making and using the same to support weight loss and/or maintenance
AssigneeLumen Bioscience, Inc.
InventorsJames Michael Roberts, Mesfin Mulugeta Gewe, Uland Lau, Mark Heinnickel, Michael Dodds, David Bolick, Nhi Yen Khuong, Hannah Tabakh, Brian Finrow, Jennifer Lynn Wierman
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Abstract
Provided are compositions comprising leptin and methods of using the same to support weight loss. Also provided are modified leptins, including recombinant leptins, and methods of making and using the same.
Claims29
A recombinant leptin receptor agonist comprising an amino acid sequence having at least about 80% sequence identity with SEQ ID NO:
- 56.
A recombinant leptin receptor agonist comprising an amino acid sequence having at least 95% sequence identity with a sequence selected from the group consisting of SEQ ID NO:
- 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, and 64.
Dependencies are inferred from the claim text.