Method for producing peptide compound
AssigneeNissan Chemical Corporation
InventorsAkihiro Nagaya, Michiharu Handa, Yuji Mimori
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AssigneeNissan Chemical Corporation
InventorsAkihiro Nagaya, Michiharu Handa, Yuji Mimori
Estimating the term…
The invention provides a method for producing a peptide by (1) removing the N-terminal protective group of an amino acid or peptide compound of formula (I): wherein Y represents a residue of an N-protected amino acid or an N-protected peptide, and each of R1, R2, and R3 independently represents an aliphatic hydrocarbon group which may have a substituent or an aromatic hydrocarbon group which may have a substituent, wherein the total number of carbon atoms in the R1R2R3Si group is 18 to 80, and the R1R2R3SiCH2CH2 group is bonded to the C-terminus of the amino acid or peptide residue in Y; and (2) causing condensation of an N-protected amino acid or an N-protected peptide and the N-terminus of the C-protected amino acid or C-protected peptide obtained in the step (1).
A method for producing a peptide, comprising the steps of:
A method for producing a peptide, comprising the steps of:
A compound represented by the following formula (IV):
A compound represented by the following formula (IV):
A compound represented by the following formula (IV):
A compound represented by the following formula (V):
A compound represented by the following formula (V′):
A compound represented by the following formula (V″):
A compound represented by the following formula (V′″):
Dependencies are inferred from the claim text.