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US 12,466,795 B2Granted
Isoindoline compositions and methods for treating neurodegenerative disease
AssigneeCognition Therapeutics, Inc.
InventorsGilbert M. Rishton, Susan M. Catalano, Gary C. Look
Life of this patent
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Abstract
Isoindoline sigma-2 receptor antagonist compounds, pharmaceutical compositions comprising such compounds, and methods for inhibiting Abeta-associated synapse loss or synaptic dysfunction in neuronal cells, modulating an Abeta-associated membrane trafficking change in neuronal cells, and treating cognitive decline associated with Abeta pathology are provided.
Claims6
A pharmaceutical composition comprising 10 to 2000 mg of a compound of the Formula:
- or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier or excipient.
Dependencies are inferred from the claim text.