Long-acting low-addiction HNK derivative and preparation method therefor

A compound represented by Formula I, or a salt, stereoisomer or tautomer thereof:

• wherein,
• m is an integer from 0 to 3, and n is an integer from 0 to 4;
• R1 and R2 are each independently one or more selected from a group consisting of H, halogen, hydroxyl, amino, cyano, substituted or unsubstituted C1-C6 alkyl group, substituted or unsubstituted C2-C6 alkenyl group, substituted or unsubstituted C2-C6 alkynyl group, substituted or unsubstituted C3-C10 cycloalkyl group, substituted or unsubstituted C2-C10 heterocyclic group, substituted or unsubstituted C1-C6 alkoxy group, substituted or unsubstituted mono- and di-C1-C6 alkylamino group, substituted or unsubstituted aryl group, and substituted or unsubstituted heteroaryl group;
• R3 is halogen;
• R4 is selected from a group consisting of H, substituted or unsubstituted C1-C6 alkyl group, substituted or unsubstituted C1-C8 acyl group, substituted or unsubstituted arylacyl group, and substituted or unsubstituted heteroarylacyl group;
• R5 is selected from a group consisting of substituted or unsubstituted C3-C10 cycloalkylene group, substituted or unsubstituted C2-C10 heterocyclylene group, substituted or unsubstituted arylene group, and substituted or unsubstituted heteroarylene group;
• R6 and R7 are independently selected from a group consisting of H, substituted or unsubstituted C1-C6 alkyl group, substituted or unsubstituted C2-C6 alkenyl group, substituted or unsubstituted C2-C6 alkynyl group, substituted or unsubstituted C3-C10 cycloalkyl group, substituted or unsubstituted C2-C10 heterocyclic group, substituted or unsubstituted aryl group, substituted or unsubstituted heteroaryl group, substituted or unsubstituted C1-C8 acyl group, substituted or unsubstituted arylacyl group, and substituted or unsubstituted heteroaryl acyl,
• or R6 and R7, together with N atom to which R6 and R7 are connected, form a substituted or unsubstituted 3 to 10-membered monocyclic or bicyclic structure,
• wherein a group is substituted means that the group is substituted by a substituent selected from OH;
• NH2;
• C1-C10 alkyl, alkenyl or alkynyl group;
• C1-C10 alkylamine group;
• sulfhydryl group;
• C1-C10 alkylsulfhydryl group;
• C1-C20 alkoxy group;
• C1-C10 carbonyl group;
• C3-C10 cycloalkyl group;
• 3 to 10-membered heterocyclic group with one or more heteroatoms selected from N, S, O and P;
• C6-C20 aryl group;
• C2-C20 heteroaryl group;
• nitrocyano;
• and halogen.