US 12,466,779 B2 · Method for obtaining oleacein and oleomissional type secoiridoids and for producing respective pharmaceutical preparations

Abstract

The present invention relates to a method for obtaining in pure form or in a mixture the oleacein and oleomissional substances from olive fruits and leaves and certain derivatives thereof, the bioactive diol forms, by selective extraction of specially selected leaves or fruits with water or organic solvents. It also relates to pharmaceutical preparations containing the above substances in various combinations and the therapeutic properties of these preparations for the treatment of cancer, degenerative diseases of the central nervous system, diabetes, hyperlipidemia, inflammatory diseases and the prevention of creation of atherosclerotic plaques and thrombi.

Claims14

Dependent claims

A method for obtaining secoiridoids of type

according to which:
plant material from the species Olea europaea L, including all subspecies and cultivars, is brought into contact with a solvent, said solvent comprising water or a water immiscible organic solvent, at a ratio ranging from 1:1 to 1:20 at a temperature of 15-40° C., left in contact for a time period ranging from 30 minutes to 12 hours, to activate at said temperature a reaction of an enzyme with oleuropein, said enzyme and oleuropein present in said plant material, and generate a mixture (A).

Dependencies are inferred from the claim text.

Method for obtaining oleacein and oleomissional type secoiridoids and for producing respective pharmaceutical preparations

Life of this patent

Method for obtaining oleacein and oleomissional type secoiridoids and for producing respective pharmaceutical preparations

Life of this patent

Abstract

Claims14