Loading patent…
AssigneeGenetic S.P.A.
InventorsGiuseppe Caliendo, Giuseppe Cirino, Ferdinando Fiorino, Francesco Frecentese, Marcelo Nicolas Muscarà, Elisa Perissutti, Antonio Petti, Fiorentina Roviezzo, Vincenzo Santagada, Beatrice Severino, Elisa Magli
Estimating the term…
The present invention relates to salts of budesonide 21-phosphate with β2 adrenergic agonists, preferably with formoterol, pharmaceutical compositions containing the same and the use thereof in the treatment of respiratory inflammatory pathologies, obstructive pathologies and allergen-induced airway dysfunctions. The invention further relates to the process for preparing said salts.
A salt of budesonide 21-phosphate with a β2 adrenergic agonist, wherein the β2 adrenergic agonist is Formoterol, which is in crystalline form IV characterized by an X-ray powder diffraction spectrum, which is obtained by using CuKα radiation and represented by °2θ angle, having characteristic peaks at about 5.82, 8.21, 11.67, 13.02, 13.54, 14.17, 14.87, 16.40, 16.92, 18.39, 19.69, 20.15, 20.65, 21.41, 22.28, 23.41, 23.69, 24.16, 24.77, 25.27, 26.41, 27.38, 27.84, 28.58, 30.15, 31.69, 33.58, 34.41, 35.47, 36.02, 37.59, 38.63 2theta±0.20 degrees.
Dependencies are inferred from the claim text.