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US 12,465,596 B2Granted
Stabilisation and controlled-release systems for medicaments unstable on sterilisation
AssigneeFidia Farmaceutici S.P.A.
InventorsCristian Guarise, Carlo Pizzocaro
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Abstract
Disclosed are alkenylamides of sulfated hyaluronic acid and their use for the stabilisation and release of medicaments in the form of micellar suspensions which can be administered locally and/or locoregionally, in particular intra-articularly.
Claims13
Sulfated hyaluronic acid amides (HAS) with C4-C20 alkenylamines, wherein a molar degree of derivatization of the alkenylamine in the sulfated hyaluronic acid amide ranges from 2 to 20%.
Dependencies are inferred from the claim text.