Functional fibrous material comprising microbial flakes, methods of preparing and uses thereof
AssigneeShenkar Engineering Design Art
InventorNir Debotton
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Abstract
The present disclosure provides functional fibrous material comprising fibers associated with hydrogel containing micro-flakes. The present disclosure also provides a method of forming hydrogel micro-flakes having embedded therein at least one microorganism and a method of preparing functional fibrous material, both methods comprise a step of subjecting a mixture of hydrogel and microbial material to high shear forces to form micro-flakes comprising the hydrogel with at least one microorganism embedded therein. Further provided is a method of treatment of a target comprising contacting the target with the disclosed functional fibrous material as well as the micro-flakes disclosed herein.
Claims19
A functional fibrous material, comprising:
- a plurality of fibers;
- a plurality of micro-flakes;
- wherein each micro-flake of the plurality of micro-flakes is composed of a hydrogel;
- wherein the hydrogel is crosslinked;
- wherein at least one microorganism is embedded in the hydrogel;
- wherein each micro-flake of the plurality of micro-flakes has at least one sheet-like protruding edge;
- wherein a plurality of sheet-like protruding edges of the plurality of micro-flakes are, at least partially, wrapped around the plurality of fibers so that the plurality of micro-flakes are entangled with the plurality of fibers;
- and
- wherein, when in a presence of electrolytes, the at least one microorganism is released from the functional fibrous material.
A method of forming a hydrogel, comprising:
- suspending at least one microorganism in a solution comprising gel forming material to form a microbial mixture;
- adding to the microbial mixture a sufficient amount of a crosslinking agent to cause crosslinking of the gel forming material with the at least one microorganism to form a hydrogel having the at least one microorganism embedded therein;
- and
- subjecting the hydrogel to a high shear force to form a plurality of micro-flakes, each having at least one sheet-like protruding edge of an irregular shape.
A method of treatment, the method comprising:
- contacting a skin surface to be treated with a functional fibrous material for a sufficient duration so as to result in at least one of:
- a treatment of any one of acne, seborrhea, atopic dermatitis, ammonia dermatitis, psoriasis, or rosacea,
- a treatment of a skin burn,
- a treatment of a skin infection,
- a wound healing,
- a wound care,
- a cosmetic use, or
- any combination thereof;
- wherein the functional fibrous material comprises:
- a plurality of fibers and
- a plurality of micro-flakes;
- wherein each micro-flake of the plurality of micro-flakes is composed of a hydrogel;
- wherein at least one microorganism is embedded in the hydrogel;
- and
- wherein each micro-flake of the plurality of micro-flakes has at least one sheet-like protruding edge;
- and
- wherein a plurality of sheet-like protruding edges of the plurality of micro-flakes are, at least partially, wrapped around the plurality of fibers so that the plurality of micro-flakes are entangled with the plurality of fibers.
Dependencies are inferred from the claim text.