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US 12,459,896 B2Granted
Process for preparing 4-methyl-2-propan-2-yl-pyridine-3-carbonitrile
AssigneeAmgen Inc.
InventorsAustin Gerald Smith, Padmini Kavuru Ananthoji, Peter Dornan, Xijie Dai
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Abstract
Provided herein are processes for preparing Compound A or a salt thereof, comprising admixing Compound B or a salt thereof and crotonaldehyde in the presence of an acid catalyst and a solvent to form Compound A
Claims22
A process for preparing Compound A or a salt thereof
- comprising:
- admixing Compound B
- or a salt thereof, and crotonaldehyde in a solvent and in the presence of a catalytic reagent;
- wherein the catalytic reagent comprises an acid catalyst, an organocatalyst, or a combination thereof.
1 more element
Dependencies are inferred from the claim text.