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US 12,458,673 B2Granted
Use of specific phages for the treatment of nontuberculosis mycobacteria (NTM) infections
AssigneeUniversity of Pittsburgh—Of the Commonwealth System of Higher Education
InventorsGraham F. Hatfull, Carlos Andres Guerrero, Rebekah Marie Dedrick
Life of this patent
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Abstract
Disclosed herein are compositions comprising bacteriophages and methods of using these compositions for treating NTM infections. The present disclosure also provides compositions for screening bacteriophages that are effective in treating NTM infections and methods of using the same.
Claims1
A composition comprising:
- bacteriophages BPsΔ33HTH-HRM10, Muddy, ZoeJΔ45;
- and
- one or more bacteriophages selected from Adephagia, Adjutor, Alma, BPs, BPsΔ33, BPsΔ33HTH_HRM10, BPs_HRM2, BPsΔ33HTH_HRMGD03 BPsΔ33HTH HRMGD10 Bxb1, Cain, Charlie, Che9c, D29, Elmo_HRMsmeg, FionnbharthΔ45Δ47, Fred313_cpm1, Isca, Isca_HRMsmeg Itos, Island3, Jeon, Larva, Muddy_HRMGD04, Nanosmite, Peaches, Pegleg, ZoeJ, and Faith1Δ38-40.
Dependencies are inferred from the claim text.