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US 12,458,655 B2Granted
Compositions for use in the prevention or treatment of necrotizing enterocolitis in infants or young children born by C-section
AssigneeSociete des Produits Nestle S.A.
InventorPer Torp Sangild
Life of this patent
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Abstract
The present invention relates to a composition comprising at least one human milk oligosaccharide and/or a precursor thereof, for use in preventing and/or treating necrotizing enterocolitis in infants or young children born by C-section.
Claims14
A method for achieving at least one result selected from the group consisting of improving gut protection against microbial and pathogen overgrowth, promoting gut development and maturation, decreasing gut inflammation, and promoting enteral feeding tolerance, in an infant or young child born by C-section, the method comprising:
- administering an effective amount of a composition comprising a mixture of human milk oligosaccharides to the infant or young child born by C-section,
- the mixture comprising:
- 2′-fucosyllactose (2FL) that is 60 to 70 wt. % of the mixture of human milk oligosaccharides;
- lacto-N-tetraose (LNT) and lacto-N-neotetraose (LNnT) that are 20 to 30 wt. % of the mixture of human milk oligosaccharides and in a ratio of LNT:LNnT between 2:1 and 1:1;
- and
- 6′ sialyllactose (6SL) that is 10 to 20 wt. % of the mixture of human milk oligosaccharides,
- wherein the composition does not contain any galactooligosaccharides (GOS) other than the LNT and the LNnT.
4 more elements
Dependencies are inferred from the claim text.