Cytometric assays
AssigneeThe Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
InventorsIlan Volovitz, Merav Lustgarten, Zvi Ram, Netanel Yakov Shapira, Idan Ben Horin, Gil Diamant
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Abstract
Provided relates to the field of cytometry, specifically to flow cytometric methods and kits for improved diagnosis, prognosis and monitoring of tumors and other lesions involving immune cell infiltration. Further provided are embodiments of the subject matter which relate to compositions and methods providing high resolution quantitative means for immunophenotyping and immune modeling, and for identification of disease prognostic and therapy predictive biomarkers.
Claims14
A kit for identifying innate immune cell populations in a human tissue sample, comprising a distinguishably distinct fluorescent viability dye and distinguishably distinct fluorophore-labeled antibodies directed to human CD45, CD11b, CD14, HLA-DR, and CD16 and wherein said distinguishably distinct fluorophore-labeled antibody directed to human CD45 comprises a fluorophore with a staining index of at least 200;
- and optionally a distinguishably distinct fluorophore-labeled antibody directed to CD33.
Dependencies are inferred from the claim text.