Mesh for dissolution test
AssigneeShionogi & Co., Ltd.
InventorsKensuke Horiuchi, Satoyo Matsuura, Maki Okabe
Life of this patent
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Abstract
When the mesh is placed under the bottom of a blade and over the bottom of a vessel in the dissolution test assembly equipped with either a vessel specified in the dissolution test method of the Japanese Pharmacopoeia, the United States Pharmacopoeia or the European Pharmacopoeia or a vessel used for the dissolution test, and a paddle formed from a blade and a shaft, and the suspensions and the solid dosage forms are added to or placed at the said mesh, a drug dissolves from the said dosage forms and the dissolution ratio variation between the said multiple same dosage forms can be small.
Claims8
A method of preventing coning of a suspension or a solid dosage form selected from the group consisting of a suspension, a syrup, a tablet, a capsule, a granule and a pill in a dissolution test of the suspension or the solid dosage form, the method comprising:
- using one single-layer mesh for the test,
- placing the one single-layer mesh under a bottom of a blade and above a bottom of a vessel in a dissolution test assembly comprising the vessel used in the dissolution test, and a paddle comprising the blade and a shaft, wherein the paddle has a rotating speed of 10 to 30 rpm, and
- placing the suspension or the solid dosage form on the one single-layer mesh.
Dependencies are inferred from the claim text.