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US 12,455,240 B2Granted
Method and apparatus for rapid detection of bacterial contamination
AssigneeUniversity of Maryland, Baltimore County
InventorsGovind Rao, Yordan Kostov, Mustafa Al-Adhami, Chandrasekhar Gurramkonda
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Abstract
A device and method for detecting the presence of bacteria in a sample are provided. A multi-step process for sample preparation is utilized and a microfluidic device is disclosed. The detection is performed using microfluidics and physical changes in multiple samples in differential mode.
Claims16
A kinetic fluorometer system, said system comprising:
- an excitation module comprising a light source and a voltage-controlled current source;
- a microfluidic cassette;
- an excitation filter mounted between the light source and the microfluidic cassette;
- a detector positioned 90° relative to an excitation light path from the light source;
- an emission filter positioned between the detector and the microfluidic cassette;
- and
- a microprocessor,
- wherein the microfluidic cassette comprises at least two channels, wherein a first channel is communicatively connected to at least one sample-derived negative control chamber and a second channel is communicatively connected to a sample chamber, wherein the cassette further comprises at least one inlet injection port and each channel has a dedicated outlet injection port.
5 more elements
Dependencies are inferred from the claim text.