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US 12,454,670 B2Granted
Fixed bed sampler and related methods
AssigneeUnivercells Technologies S.A.
InventorsJosé Castillo, Bastien Mairesse, Alex Chatel, Sebastien Jean-Pierre Michel Rodriguez, Alexandre Vanhaver
Life of this patent
Estimating the term…
Abstract
A sampler for use with a bioreactor for growing a cell culture is disclosed. In one embodiment, the bioreactor includes a structured fixed bed including a removable sample portion for recovering a sample of cells from the cell culture. Related apparatuses and methods are also disclosed.
Claims17
An apparatus for use with a cell culture system, comprising:
- a structured fixed bed comprising a plurality of layers of material adjacent to each other;
- and
- a removable sample portion for recovering a sample of cells from the cell culture system;
- wherein the removable sample portion comprises a perforated or pre-cut portion of one of the plurality of layers of the structured fixed bed.
1 more element
An apparatus for use with a bioreactor for growing a cell culture, comprising:
- a fixed bed comprising a plurality of layers of material adjacent to each other;
- and
- a removable sample portion forming a portion of the fixed bed, the removable sample portion including perforations adapted for detachment of the removable sample portion from a first layer of the fixed bed so as to separate the removable sample portion from a remainder of the first layer.
An apparatus for sampling a cell culture, comprising:
- a bioreactor including a structured fixed bed including a plurality of layers of woven material;
- a removable sample portion, wherein the removable sample portion forms a portion of a first of the plurality of layers, and wherein the removable sample portion includes a pre-cut or perforated piece of the portion of the first of the plurality of layers for detachment from a remainder of the first of the plurality of layers of the structured fixed bed.
Dependencies are inferred from the claim text.