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US 12,454,556 B2Granted
Fusion polypeptides for target peptide production
OwnerChristoph Kutznerinventor
Life of this patent
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Abstract
The present invention relates to fusion polypeptides, nucleic acid molecules encoding such fusion polypeptides and genetically modified cells comprising such nucleic acid molecules. Additionally, the present invention relates to a method for preparing a target peptide and target peptide mixtures.
Claims9
A fusion polypeptide comprising in direction from the N-terminus to the C-terminus:
- (i) a first domain comprising the amino acid sequence selected from the group consisting of SEQ ID NOs:
- 1-9;
- (ii) a second domain comprising the amino acid sequence that is at least 90% identical to the amino acid sequence of SEQ ID NO:
- 117;
- and (iii) a target peptide domain.
2 more elements
A fusion polypeptide comprising in direction from the N-terminus to the C-terminus:
- (i) a purification domain comprising the amino acid sequence selected from the group consisting of SEQ ID NOs:
- 10-116, wherein the purification domain binds to a carbohydrate matrix;
- (ii) an autoprotease domain comprising the amino acid sequence selected from the group consisting of SEQ ID NOs:
- 118-120;
- and (iii) a target peptide domain.
2 more elements
Dependencies are inferred from the claim text.