Packaging system for small-volume aseptic filling

A packaging system for sealing a medicine container, the packaging system comprising:

• a container tray having a container cell for releasably securing the medicine container;
• and
• a stopper clip having a stopper cell for releasably securing a stopper, the stopper clip comprising a first hinged-base leg, a second hinged-base leg, and a hinge joining the first hinged-base leg and the second hinged-base leg, wherein:
• the hinge is biased to urge the first hinged-base leg and the second hinged-base leg toward one another,
• the first hinged-base leg has a first pushing surface configured to contact a proximal surface of the stopper when the stopper is releasably secured in the stopper cell,
• the second hinged-base leg has a second pushing surface configured to contact the proximal surface of the stopper when the stopper is releasably secured in the stopper cell,
• the first hinged-base leg has a first radially extending retention arm that is distal of the first pushing surface,
• the second hinged-base leg has a second radially extending retention arm that is distal of the second pushing surface, and
• the first radially extending retention arm and the second radially extending retention arm together are configured to prevent distal movement of the stopper when the stopper is releasably secured in the stopper cell.

A packaging system for sealing a plurality of medicine containers, the packaging system comprising:

• a container tray having a plurality of container cells for releasably securing the plurality of medicine containers;
• and
• a stopper clip having a plurality of stopper cells for releasably securing a plurality of stoppers, the stopper clip comprising a first hinged-base leg, a second hinged-base leg, and a hinge joining the first hinged-base leg and the second hinged-base leg,
• wherein:
• the first hinged-base leg has a first lever extending therefrom,
• the second hinged-base leg has a second lever extending therefrom,
• the hinge is biased to urge the first hinged-base leg and the second hinged-base leg toward one another to a first position,
• the first lever and the second lever are spaced from one another such that, upon application of a first compressive force to the first lever and the second lever to apply force about the hinge, the first hinged-base leg and the second hinged-base leg are configured to move to a second position in which the first hinged-base leg and the second hinged-base leg are spaced apart to allow insertion of the plurality of stoppers between the first hinged-base leg and the second hinged-base leg, and
• upon removal of the first compressive force to the first lever and the second lever, the first hinged-base leg and the second hinged-base leg are configured to move to a third position in which the first hinged-base leg and the second hinged-base leg releasably secure the plurality of stoppers between the first hinged-base leg and the second hinged-base leg.