# US 12,453,869 B2 · Systems, methods and software for magnetic resonance image guided radiotherapy > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,453,869 B2 - Document ID: US12453869B2 - Status: Granted - Kind: B2 - Application number: 18/491,527 - Filed: 2023-10-20 - Published: 2024-06-13 - Granted: 2025-10-28 - Earliest claimed: 2022-10-20 - Assignees: ViewRay Systems, Inc. - Applicants: ViewRay Systems, Inc. - Inventors: James F. Dempsey; Iwan Kawrykow - Web page: https://patentgrep.com/patent/US12453869B2 ## CPC - A61N 5/1039: {using functional images, e.g. PET or MRI} - G16H 20/40: relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture - A61N 5/1037: {taking into account the movement of the target, e.g. 4D-image based planning} - A61N 5/107: {in real time, i.e. during treatment} - A61N 2005/1041: {using a library of previously administered radiation treatment applied to other patients} - A61N 2005/1055: {using magnetic resonance imaging [MRI]} - A61N 2005/1072: {taking into account movement of the target} - A61N 2005/1074: {Details of the control system, e.g. user interfaces} - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) - G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA ## Abstract Systems, methods, and computer software are disclosed that can include receiving a treatment prescription for a patient, obtaining a diagnosis-driven magnetic resonance imaging guided radiotherapy treatment and planning workflow (MRgRT&P workflow) associated with the treatment prescription from a workflow library, the diagnosis-driven MRgRT&P workflow having a parameter list comprising parameters utilized for MRI-guided radiation therapy. With the diagnosis-driven MRgRT&P workflow, any of the following can be performed: imaging with the MRI-guided radiation therapy system utilizing radiation therapy imaging parameters in the parameter list, generating a radiation therapy treatment plan utilizing radiation therapy planning parameters in the parameter list, and/or controlling an MRI-guided radiation therapy system utilizing radiation therapy delivery parameters in the parameter list. ## Claims ### Claim 1 A system comprising: at least one programmable processor; and a non-transitory machine-readable medium storing instructions which, when executed by the at least one programmable processor, cause the at least one programmable processor to perform operations comprising: receiving a treatment prescription for a patient; obtaining, from a workflow library, a diagnosis-driven magnetic resonance imaging guided radiotherapy treatment and planning workflow (MRgRT&P workflow) associated with the treatment prescription, the diagnosis-driven MRgRT&P workflow having a parameter list comprising parameters utilized for MRI-guided radiation therapy; imaging with an MRI-guided radiation therapy system utilizing radiation therapy imaging parameters in the parameter list; generating a radiation therapy treatment plan utilizing radiation therapy planning parameters in the parameter list; and controlling an MRI-guided radiation therapy system utilizing radiation therapy delivery parameters in the parameter list. ### Claim 2 (depends on 1) The system of claim 1, wherein the treatment prescription includes disease type, treatment site, stage, total dose, number of fractions, dose per structure per fraction, min/max/mean dose constraints and/or dose volume constraints for targets and organs. ### Claim 3 (depends on 1) The system of claim 1, the obtaining of the diagnosis-driven MRgRT&P workflow comprising: comparing the treatment prescription to stored treatment prescriptions associated with stored diagnosis-driven MRgRT&P workflows; and returning a stored diagnosis-driven MRgRT&P workflow with a stored treatment prescription that matches the treatment prescription. ### Claim 4 (depends on 1) The system of claim 1, wherein the radiation therapy planning parameters include one or more of: anatomy identification parameters, autocontouring parameters or relative electron density parameters. ### Claim 5 (depends on 1) The system of claim 1, wherein the radiation therapy planning parameters include one or more of: volumetric imaging parameters, image registration parameters, anatomy segmentation parameters, treatment planning parameters, treatment plan dose computation parameters, treatment plan optimization parameters, dose display parameters or treatment option parameters. ### Claim 6 (depends on 1) The system of claim 1, wherein the radiation therapy imaging parameters include one or more of: volumetric imaging parameters, planar imaging parameters or tissue tracking parameters. ### Claim 7 (depends on 1) The system of claim 1, wherein the radiation therapy delivery parameters include one or more of: beam energy, MLC positions, or couch positions. ### Claim 8 (depends on 1) The system of claim 1, the operations further comprising requesting user confirmations relating to the generating, imaging and/or controlling based on the parameter list. ### Claim 9 (depends on 1) The system of claim 1, the operations further comprising provision of a workflow editor configured to facilitate revision of the diagnosis-driven MRgRT&P workflow. ### Claim 10 (depends on 1) The system of claim 1, the operations further comprising: obtaining, from the workflow library, an additional diagnosis-driven magnetic resonance imaging guided radiotherapy treatment and planning workflow (MRgRT&P workflow) associated with the treatment prescription; and presenting a user with multiple diagnosis-driven MRgRT&P workflows to choose from.