Modulators of rho-associated protein kinase
AssigneeRedx Pharma PLC
InventorsClifford D. Jones, Peter Bunyard, Gary Pitt, Liam Byrne, Thomas Pesnot, Nicolas E. S. Guisot
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Abstract
This invention relates to novel compounds and pharmaceutical compositions comprising. Compounds of the invention useful as modulators of Rho-associated protein kinase (ROCK), for example ROCK1 and/or ROCK2 inhibitors. Methods of treatment employing the compounds are also contemplated by the present invention. The compounds of the invention are useful in treating ROCK mediated diseases.
Claims10
A compound, wherein the compound is:
- or a pharmaceutically acceptable salt thereof.
A compound, wherein the compound is:
A method of treating a condition selected from the group consisting of:
- fibrotic diseases, auto-immune, inflammatory-fibrotic conditions, inflammatory conditions, central nervous system disorders, and cancer, wherein the method comprises administering to a patient in need thereof a therapeutic amount of a compound which is:
- or a pharmaceutically acceptable salt thereof.
A method of treating a condition selected from the group consisting of:
- fibrotic diseases, auto-immune, inflammatory-fibrotic conditions, inflammatory conditions, central nervous system disorders, and cancer, wherein the method comprises administering to a patient in need thereof a therapeutic amount of a compound which is:
Dependencies are inferred from the claim text.