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US 12,453,688 B2Granted
Cosmetic compositions comprising dragline spider silk
AssigneeSeevix Material Sciences Ltd.
InventorsKonstantin Press, Gregory Idelson, Ariel Givant, Alon Meir, Noa Hadar
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Abstract
Cosmeceutical compositions comprising a major ampullate spidroin protein (MaSp)-based fiber are disclosed. Articles comprising the compositions are further disclosed.
Claims6
A cosmeceutical composition comprising a cosmeceutical effective amount of a composite, wherein the composite comprises a derivatized porous major ampullate spidroin protein (MaSp)-based fiber bound to a metal oxide particle, wherein:
- said metal oxide particle is characterized by a particle size between 10 and 900 nm;
- said derivatized porous MaSp-based fiber is insoluble in an aqueous solution;
- said derivatized porous MaSp-based fiber is in a form of particles having an average particle size between 0.5 μm and 1.5 μm and is characterized by a BET surface area of at least 10 m2/g;
- said derivatized porous MaSp-based fiber comprises a functional moiety covalently bound to a tyrosine of the derivatized porous MaSp-based fiber via a diazo bond;
- said functional moiety comprises a polymer bound to a plurality of metal oxide chelating groups;
- said metal oxide particle is bound to the derivatized porous MaSp-based fiber via said metal oxide chelating groups.
3 more elements
Dependencies are inferred from the claim text.