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US 12,448,359 B2Granted
Compounds with immunomodulatory activity and therapeutic uses thereof
AssigneePurdue Research Foundation
InventorsGaurav Chopra, Prageeth Wijewardhane, Krupal P. Jethava, Jonathan Fine
Life of this patent
Estimating the term…
Abstract
The present invention generally relates to new compounds for therapeutic uses. In particular, the disclosed series compounds with immunomodulatory activities are useful for treatment of dysfunctions of the immune system and various cancers. Pharmaceutical composition matters and methods for treating a patient with an immune disease and/or a cancer by administering therapeutically effective amounts of such compound alone or together with other therapeutics are within the scope of this disclosure.
Claims7
A compound having the formula (I):
- or a pharmaceutically acceptable salt thereof, wherein
- Ar1 is 2,3-dihydrobenzo [b] [1,4]-dioxinyl;
- R1 and R2 are each, independently, alkyloxy;
- R3 is alkyl;
- and
- Q is
3 more elements
Dependencies are inferred from the claim text.